The Hale Vaccine was a cure for the Chimeran virus created by Dr. Fyodor Malikov that was based on Pure Chimeran blood extracted from the body of Nathan Hale. Malikov discovered a unique protein within Hale's blood which he isolated and successfully cultivated into a vaccine for the Chimeran virus. Apparently, the Hale Vaccine was produced on a large enough scale for distribution to the surviving human population.
The vaccine also enabled Sentinels to survive without inhibitor treatments, but caused the downside of losing their regenerative abilities. Joseph Capelli was among those who were vaccinated with the vaccine.
- The Hale Vaccine is may be the explanation why human survivors have begun to use Chimeran Sym-Bac fluid as medication, reducing the number of human casualties as seen in throughout Resistance 3, and can be observed in by human settlements in Haven and Mount Pleasant.